Image by Gabriele Diwald

Publications

 

Publication of Latest Findings

  • Dawei Xu, Samuel Lim, Yuhong Cao, Abner Abad, Aubrey Nayeon Kang and Douglas S.Clark, "Filamentous Chaperone Protein-Based Hydrogel Stabilizes Enzymes Against Thermal Inactivation". Chemical Communications, 2021, 57, 5511-5513.

  • Yuhong Cao, George F. Gao,"mRNA Vaccines: A Matter of Delivery". EClinicalMedicine, 32 (2021) 100746.

  • Huan Zhang#,Yu.hong Cao# (Equal Contribution), Dawei Xu, Natalie S. Got, Gozde S. Demirer, Stefano Cestellos-Blanco, Yuan Chen, Makita Landry*, Peidong Yang*, “Gold Nanoclusters Meditated Delivery of siRNA to Intact Plant Cells for Efficient Gene Knockdown”. Nano Letters, Accepted.


  • Zhongwen Chen#, Yuhong Cao# (Equal contribution), Chun-Wei Lin, Steven Alvarez, Dongmyung Oh, Peidong Yang*, Jay Groves*, “Nanopore Mediated Protein Delivery Enabling 3-color Single Molecule Tracking in Living Cells”, Proceedings of the National Academy of Sciences, 2021, Vol. 118 No. 5 e2012229118.

  • Yude Su*, Stefano Cestellos-Blanco*, Ji Min Kim*, Yue-xiao Shen, Qiao Kong, Dylan Lu, Chong Liu, Hao Zhang, Yuhong Cao, Peidong Yang, “Close-packed nanowire-bacteria hybrids for efficient solar-driven CO2 fixation”, Joule, 4, 800–811 (2020).


  • Yuhong Cao, Enbo Ma, Stefano Cestellos-Blanco, Bei Zhang, Ruoyi Qiu, Yude Su, Jennifer A. Doudna, and Peidong Yang, “Nontoxic Nanopore Electroporation for Effective Intracellular delivery of Biological Macromolecules”, Proceedings of the National Academy of Sciences, Apr 2019, 116 (16) 7899-7904.


  • Yuhong Cao, Haodong Chen, Ruoyi Qiu, Enbo Ma, Richard Lewis, Joseph C. Wu, Nicholas A. Melosh, “Universal Biomolecules Intracellular Delivery with Dosage Quantitative Control” Science Advances, 2018, 4, 10.


  • Gen He, Hui-Jiuan Chen, Di liu, Yuping Feng, Chengduan Yang, Tian Hang, Jiangming Wu, Yuhong Cao, Xie Xi, ‘Fabrication of Various Structures of Nanostraw Arrays and Their Applications in Gene Delivery” Advanced Materials Interfaces, 2018, 5, 1701535.

  • Tian Hang, Hui-Jiuan Chen, Ji Wang, Di-An Lin, Jiangming Wu, Yuhong Cao, Chengduan Yang, Chenglin Liu, Shuai Xiao, Meilin Gu, Shuolin Pan, Mei Wu, Xi Xie “Nanospikes Functionalization as a Universal Strategy to Disperse Hydrophilic Particles in Non-polar Media" Nanotechnology, 2018, 29, 18. 


  • Bozhi Tian, Shuai Xu, John Rogers, Stefano Cestellos-Blanco, Peidong Yang, Joao L Carvalho-de-Souza, Francisco Bezanilla, Jia Liu, Zhenan bao, Martin Hjort, Yuhong Cao, Nicholas Melosh, Guglielmo Lanzani, Fabio Benfenati, Giulia Galli, Francois Gygi, Rylan Kautz, Alon A Gorodetsky, Samuel S Kim, Timothy K Lu, Polina Anikeeva, Michal Cifra,Ondrej Krivosudsky, Daniel Havelka and Yuanwen Jiang. “Roadmap on semiconductor-cell biointerfaces” Physical Biology, 2018, 15, 031002.


  • Yuhong Cao, Martin Hjort, Haodong Chen, Fikri Birey, Sergio Leal-Ortiz, Crystal M. Han, Juan G. Santiago, Sergiu P. Pașca, Joseph C. Wu, Nicholas A. Melosh, “Non-Destructive Nanostraw Intracellular Sampling for Longitudinal Cell Monitoring” Proceedings of the National Academy of Sciences, 2017, 114 (10) E1866-E1874.[Highlight by Science, Cozzarelli Award by National Academy of Sciences (Annual best paper of PNAS)].


  • Alexander M. Xu, Derek Wang, Peyton Shieh, Yuhong Cao, Nicholas A. Melosh, “Direct Intracellular Delivery of Cell-Imermeable Probes of Protein Glycosylation by Using Nanostraws” ChemBioChem, 2017,18,7.


  • Yuling Liu, Yuhong Cao, Xi Xie, Meiwan Chen, Hui Li, “Redox-sensitive pluronic F127-tocopherol micelles: synthesis, characterization and cytotoxicity evaluation” ICMJE, 2017, 12, 2635-2644.


  • Cade B. Fox, Yuhong Cao, Cameron L. Nemeth, Hariharasudhan D. Chirra, Rachel W. Chevalier, Alexander M. Xu, Nicholas A. Melosh, Tejal A. Desai “Fabrication of sealed nanostraw microdevices for oral drug delivery” ACS Nano, 2016, 10, 5873-5881.

  • Xi Xie, Alex Xu, Sergio Leal-Ortiz, Yuhong Cao, Craig Garner, Nicholas A. Melosh, “Nanostraw-electroporation system for highly efficient intracellular delivery and transfection.” ACS Nano, 2013, 7, 4351−4358.

Patents and Applications

  • WO2019018415A1. APPARATUSES AND METHODS USING NANOSTRAWS TO DELIVER BIOLOGICALLY RELEVANT CARGO INTO NON-ADHERENT CELLS


  • WO2017214541A1. NANOSTRAW WELL DEVICES FOR INPROVED CELL TRANSFECTION AND VIABILITY 


  • US2019035994A1. METHODS OF NON-DESTRUCTIIVE NANOSTRAW INTRACELLULAR SAMPLING FOR LONGITUDINAL CELL MONITORING


  • WO2020069129A1. NANOPORE MEMBRANE DEVICE AND METHODS OF USE THEREOF 

  • DISCLOSURE. NANOPORE FILTER MICROFLUIDIC INJECTION DEVICE.